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[9] "AHK tripeptide demonstrated a 3.2-fold increase in collagen synthesis markers compared to control groups, with optimal effects observed at concentrations between 0.5-1.0 mg/mL." [10] Understanding these pharmacokinetic properties is crucial for dosage optimization, as subtherapeutic concentrations below 0.1 mg/mL show minimal biological activity, while concentrations exceeding 5 mg/mL may trigger inflammatory responses in sensitive individuals